QS-Hill-Negative Feedback

Name:

Author: Chris Cox

Location: University of Tennessee ccox9@utk.edu

Quality:

Description:

Species

Species	Initial Population	Output	Comment
luxD	1	false
luxDcomp	0	false
AI	0	true
LuxR	0	true
LuxI	0	true
RAI	0	true
RAI2	0	true
promI	1	false
promR	1	false
AIsource	1	false
mRNAI	0	false
mRNAR	0	false
DNAloop	0	true
ipromI	0	true
ipromR	0	false
luxbox	1	false

Basic Reactions

Name	Reaction	Rate Constant	Comment
a	AI + LuxR -> RAI	0.1
b	RAI -> LuxR + AI	2
c	2 RAI -> RAI2	.06
d	RAI2 -> 2 RAI	4
e	RAI2 + luxD -> luxDcomp	.01
f	luxDcomp -> RAI2 + luxD	3
g	luxDcomp + ipromR -> DNAloop	6
h	DNAloop -> luxDcomp + ipromR	1
i	mRNAR -> LuxR + mRNAR	0.03
j	mRNAI -> LuxI + mRNAI	0.03
k	mRNAR -> *	0.006
l	mRNAI -> *	0.006
m	LuxI -> *	0.001
n	LuxR -> *	0.006
o	LuxI -> LuxI + AI	0.017
p	AI -> *	7.1
q	AIsource -> AI + AIsource	500
r	luxbox + RAI2 + promI + promR -> ipromI + ipromR	0.1
s	ipromI + ipromR -> luxbox + RAI2 + promI + promR	5
v	promR -> promR + mRNAR	0.01
w	promI -> promI + mRNAI	0.000015
x	ipromR -> ipromR + mRNAR	0.06
y	ipromI -> ipromI + mRNAI	0.1

Hill Reactions

Name

Reaction

Vmax

Species

Comment

AI 1 LuxR 1 k RAI 1 k RAI 2 k RAI2 1 k RAI2 1 luxD 1 k luxDcomp 1 k luxDcomp 1 ipromR 1 k DNAloop 1 k mRNAR 1 k mRNAI 1 k mRNAR 1 k mRNAI 1 k LuxI 1 k LuxR 1 k LuxI 1 k AI 1 k AIsource 1 k luxbox 1 RAI2 1 promI 1 promR 1 k ipromI 1 ipromR 1 k promR 1 k promI 1 k ipromR 1 k ipromI 1 k